Home to the world’s largest private portfolio of artwork, the Vatican Museum is a must-see for visitors to Rome, and the best way to explore it is with our guide. Learn about the highlights of Vatican collections, as you explore intriguing rooms and visit the Sistine Chapel to see incredible frescoes by Michelangelo. This tour also includes a guided tour (with fast-track access entrance) to St. Peter’s Basilica The enormous St. Peter's Basilica (Basilica di San Pietro) dominates Vatican City, and its dome can be seen from all over Rome. Built on the site of St. Peter’s crucifixion and over his tomb, it’s the epicenter of the Catholic Church and the burial place of many popes, including Pope John Paul II. The lavishly adorned basilica is the largest church in Italy, and it's also a museum full of priceless works of art—including Michelangelo’s sublime Pietà and Bernini’s bronze baldachin.